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PhD Thesis

1 Pharmacophylogenomics - Explaining interspecies differences in drug discovery
T. Hulsen
Radboud University Nijmegen 2007

Scientific papers - Authorships

1 Heavier-than-air flying machines are impossible
L. Oliveira, T. Hulsen, D. Lutje Hulsik, A.C.M. Paiva and G. Vriend
FEBS Letters 2004, 564 (3): 269-273
PubMed: 15111108
(Final submitted version)
(Earlier, more extended version)
2 Benchmarking ortholog identification methods using functional genomics data
T. Hulsen, M.A. Huynen, J. de Vlieg and P.M.A. Groenen
Genome Biology 2006, 7 (4): R31
PubMed: 16613613

(Supplementary information)
3 PhyloPat: phylogenetic pattern analysis of genes
T. Hulsen, J. de Vlieg and P.M.A. Groenen
BMC Bioinformatics 2006, 7 (1): 398
PubMed: 16948844

(Web application)
4 Testing statistical significance scores of sequence comparison methods using structure similarity
T. Hulsen, J. de Vlieg, J.A.M. Leunissen and P.M.A. Groenen
BMC Bioinformatics 2006, 7 (1): 444
PubMed: 17038163

(Supplementary information)
5 Identification of novel functional TBP-binding sites and general factor repertoires
S. Denissov, M.A. van Driel, R. Voit, M.L. Hekkelman, T. Hulsen, N. Hernandez, I. Grummt, R. Wehrens and H.G. Stunnenberg
EMBO J. 2007, 26 (4): 944-954
PubMed: 17268553
6 Evolution of closely linked gene pairs in vertebrate genomes
E. Franck, T. Hulsen, M.A. Huynen, W.W. de Jong, N.H. Lubsen and O. Madsen
Mol. Biol. Evol. 2008, 25 (9): 1909-1921
PubMed: 18566020
7 PhyloPat: an updated version of the phylogenetic pattern database contains gene neighborhood
T. Hulsen, P.M.A. Groenen, J. de Vlieg and W. Alkema
Nucleic Acids Res. 2009, 37 (Database issue): D731-D737
PubMed: 18832367
(Web application)
8 BioVenn - a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams
T. Hulsen, J. de Vlieg and W. Alkema
BMC Genomics 2008, 9 (1): 488
PubMed: 18925949

(Web application)
9The construction of genome-based transcriptional units
S.R. van Hooff, J. Koster, T. Hulsen, B.D.C. van Schaik, M. Roos, M.F. van Batenburg, R. Versteeg and A.H.C. van Kampen
OMICS: A Journal of Integrative Biology 2009, 13 (2): 105-114
PubMed: 19320556

Scientific papers - Acknowledgements

1 Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor-induced Osteoblast Differentiation
O. Korchynskyi, K.J. Dechering, A. Sijbers, W. Olijve and P. ten Dijke
Journal of Bone and Mineral Research (JBMR) 2003, 18 (7): 1177-1185
PubMed: 12854827
2 A text-mining analysis of the human phenome
M.A. van Driel, J. Bruggeman, G. Vriend, H.G. Brunner, J.A. Leunissen
Eur J Hum Genet. 2006, 14 (5): 535-542
PubMed: 16493445
3 The human phylome
J. Huerta-Cepas, H. Dopazo, J. Dopazo, T. Gabaldon
Genome Biology 2007, 8: R109
PubMed: 17567924
4 Commercial harvest of logging residue in clear-cuts affects the diversity and community composition of ground beetles (Coleoptera: Carabidae)
K. Nitterus, M. Astrom, B. Gunnarsson
Scandinavian Journal of Forest Research 2007, 22 (3): 231-240
5 Plasma Membrane Proteomics
E. Alexandersson, N. Gustavsson, K. Bernfur, P. Kjellbom, C. Larsson
Plant Proteomics 2007, 186-206
6 Multiple Ionization Mass Spectrometry Strategy Used To Reveal the Complexity of Metabolomics
A. Nordstrom, E. Want, T. Northen, J. Lehtio, G. Siuzdak
Analytical Chemistry 2008, 80 (2): 421-429
PubMed: 18085752
7 LocateP: Genome-scale subcellular-location predictor for bacterial proteins
M. Zhou, J. Boekhorst, C. Francke, R.J. Siezen
BMC Bioinformatics 2008, 9 (1): 173
PubMed: 18371216

Scientific papers - Briefings

1 Abstracts
I.K. Jordan
Brief Bioinform 2006, 7 (4): 407-412

Posters

1 Connecting the proteomes of model organisms: Classification of the protein universe
T. Hulsen, P.M.A. Groenen and M.A. Huynen
ICS PhD Two-Day Conference Arnhem, 2003-05-08
Bioinformatics 2003: Bioinformatics at the Interface Utrecht, 2003-06-20
2 Protein World: Connecting the proteomes of model organisms
T. Hulsen, P.M.A. Groenen and M.A. Huynen
ECCB 2003 Paris (France), 2003-09-27 - 2003-09-30
SC2003 Phoenix (USA), 2003-11-15 - 2003-11-21
3 Conservation of chromosomal distance, relative orientation and co-expression of eukaryotic gene pairs
T. Hulsen, P.M.A. Groenen and M.A. Huynen
CMBI Conference Ravenstein, 2003-10-29
NVBMB Najaarssymposium 2003 Oss, 2003-11-05
4 Benchmarking ortholog identification methods using function similarity
T. Hulsen, P.M.A. Groenen and M.A. Huynen
ICS PhD Two-Day Conference Arnhem, 2004-04-19
5 Protein World & Orthology Benchmarking
T. Hulsen, P.M.A. Groenen, W. Fleuren and M.A. Huynen
ISMB/ECCB 2004 Glasgow (UK), 2004-08-01
6 Benchmarking ortholog identification methods using functional genomics data
T. Hulsen, P.M.A. Groenen, J. de Vlieg and M.A. Huynen
GeNeYouS Symposium Oss, 2005-04-27
ICS PhD Two-Day Conference Arnhem, 2005-04-28
7 Testing statistical significance scores of sequence comparison methods with structure similarity
T. Hulsen, J.A.M. Leunissen, J. de Vlieg and P.M.A. Groenen
NBIC Conference Ede, 2006-04-24
8 Dynamics of bidirectional gene pairs in vertebrate genomes
E. Franck, T. Hulsen, M.A. Huynen, L. Lubsen, W. de Jong, O. Madsen
Bioinformatics 2006 �hus(Denmark), 2006-06-17
9 PhyloPat: phylogenetic pattern analysis of genes
T. Hulsen, J. de Vlieg and P.M.A. Groenen
CMBI @ NCMLS Opening Nijmegen, 2006-10-09
BeNeLux Bioinformatics Conference 2006 Wageningen, 2006-10-17
10 Evolution of the immune system from model organism to man
T. Hulsen, W.W.M. Fleuren and P.M.A. Groenen
NBIC-ISNB 2007 Amsterdam, 2007-04-16
Organon MDI Retreat Heeze, 2007-06-11
11 BioRange SP 3.2.2.: Translational Medicine through Comparative Genomics and data integration
W.W.M. Fleuren, R. Frijters, T. Hulsen, P.M.A. Groenen, J. de Vlieg and W. Alkema
NBIC 2008 Lunteren, 2008-03-05
12 PhyloPat version 49 - An updated version contains gene neighborhood
T. Hulsen, P.M.A. Groenen, W. Alkema, J. de Vlieg
ISMB 2008 Toronto (Canada), 2008-07-19

Reports

1 Generation of GST-p24 fusion proteins for antisera production and p24/COP binding studies
T. Hulsen
Molecular Animal Physiology Nijmegen, 2000-08-31
2 The cAMP response element binding protein (CREB) and its role in the nervous system
T. Hulsen
Molecular Animal Physiology Nijmegen, 2000-09-30
3 GPCR Website
T. Hulsen and D. Lutje Hulsik
CMBI Nijmegen, 2001-05-31

Kennislink

1 Identificatie van genen en eiwitten
Kennislink, 2003-08-28
2 De evolutie van genen
Kennislink, 2004-02-23
3 Biologische databanken
Kennislink, 2005-05-20

Others

1 PromScan, a promoter detection and analysis tool
T. Hulsen and S. Denissov
De Verbinding, 2003-06-27
2 Academia or Industry: Making a Conscious Decision
Science Next Wave / Science Careers, 2003-07-11 (Science TOC) (Spanish) (Portuguese)
3 Werken in de bioinformatica
G-mi, 2004-02-23
4 Tim Hulsen (24) en zijn twee linkerhanden - Voetballen met eiwitten
Myrna Tinbergen
Jaarverslag KUN, 2004-07-01
5 Bioinformatics in the Netherlands: Thriving and Exciting
Science Next Wave / Science Careers, 2004-09-24 (Science TOC)
6 Eiwittendatabank kan medicijnontwikkeling helpen
Wetenschapsagenda Radboud Universiteit Nijmegen, 2007-08-15 (Index) (PDF)
 

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